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This system is for fast quantitative evaluation of SVP (sub-visible particle) aggregates from 100 nm to 10 µm in size, which may be contained in biopharmaceuticals.
“Aggregates” are collections of particles, and “sizer” refers to particle analyzers and dimensional measuring instruments. This system evaluates the existence of aggregates, for which there are concerns about shock disease and other side effects, in terms of concentration (µg/mL). It can be used for quality control and to enhance efficiency in the development of biopharmaceuticals
The highly efficient reflecting objective mirrors and an optimal optical system featuring aspherical mirrors ensure high sensitivity. Stage movements, aperture settings, and focusing can be controlled from a PC screen for exceptional ease of use.
This is a dedicated spectrophotometer for checking the concentration and purity of nucleic acid samples. It analyzes 1 to 2 µL trace samples of nucleic acids. Simply drop the sample onto the window with a pipette and press the [Start] button on the instrument or click the [Start] button on the software screen to start automatic light path setting, measurement, and wiping of samples on the window.
It is not necessary to make vertical arm adjustments or wipe the widow with a cloth. Dedicated software simplifies operation. Just click buttons on the toolbar to conduct basic operations including measurement, report printing, and exporting data.
The DTG-60 series from Shimadzu uses a parallel guide differential top pan balance mechanism that simultaneously measures temperature changes and mass changes between an inert reference and sample. Versions include high-temperature models, H models, and auto sampler models (A models) for a higher level of efficiency.
Included in the DTG-60 series:
Excellent Baseline Stability and High Sensitivity
The differential balance in the DTG-60 series is of the Roberval style, where the sample and reference are located above the balance at the top of two separate detectors. This design prevents changes in sensitivity from thermal expansion, enables high-precision thermogravimetric measurements, and minimizes baseline drifts caused by buoyancy or convection during the heating process.
Wide Measurable Mass and Differential Thermal Ranges
The advanced balance, high-quality detectors, and excellent furnace temperature distribution combine to provide a measurable mass change of ±500 mg, a mass readability of 0.1 µg, a maximum sample quantity of 1 g, and a measurable differential thermal range of ±1,000 µV.
Automated Measurement up to 24 Samples
The compact, built-in auto sampler of the DTG-60A and DTG-60AH models can hold up to 24 samples for continuous data acquisition. After setup of a master file, automatic analysis and printing is performed per the preset conditions in the template.
Integrated Cooling and Controlled Atmospheres
The built-in cooling fan and low-mass furnace combine to create quick cooling between measurements. Reactive gases are supplied directly to the sample area and an inert gas purges the balance. By incorporating a FC-60A atmosphere control unit, the software can be used to switch reactive gases during a temperature program.
Controlled by TA-60WS Thermal Analysis Workstation
The TA-60WS thermal analysis workstation connects the DTG-60 series and the computer. Intuitive data acquisition software controls the DTG-60 series and optional accessories, such as the FC-60A atmosphere control unit. In addition, the TA-60WS and data acquisition software can be used to simultaneously control up to four Shimadzu thermal analysis instruments of any type.
Software Compliant with Analytical Laboratory Regulations and US FDA 21 CFR Part 11
A software version that complies with US FDA 21 CFR Part 11, electronic record, and electronic signature (ER/ES) regulations, and PIC/S GMP guidelines is available.
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Equipped with an electronically cooled high-performance semiconductor detector, the EDX-7000/8000 is designed for reduced running costs and ease of maintenance while providing better sensitivity, throughput, and resolution than conventional models. A wealth of optional functions is available, including a vacuum measurement unit, which is effective for light element analysis, and a turret unit, which is effective for consecutive analyses. Two software programs are included as standard. PCEDX-Navi allows easy operation, and PCEDX-Pro is for general analysis applications. As an analysis option, the instrument can also be equipped with the screening functions achieved with the EDX-LE. From management applications involving compliance with RoHS/ELV directives and other environmental regulations to research applications involving the high-level needs of general sample analysis, the EDX-7000/8000 can be applied broadly, whatever the industry.
The GC-2010 Plus Series is ideal for enhancing analysis sensitivity and productivity. Excellent repeatability is assured by the optimized vaporization chamber and the electronic flow controller (AFC) that accurately controls the carrier gas up to the high-pressure, high- flowrate regions required for HPLC analysis.
The GC-2010 Plus enables reliable, high-precision trace analysis with high repeatability, utilizing detectors such as FID and FPD that feature best-in-class sensitivity. In addition, rapid oven cooling and backflush technology shorten analysis time greatly for significant improvements in productivity. A lineup of powerful detectors ensures the highest sensitivity – even for trace amount analysis. Rapid oven cooling, back flushing technology, gas saver function, etc. New flow-controlling technologies enable higher separation capability and faster analysis.
Get the high performance of the GC-2010 now also for your routine work. Based on the successful design of the GC-2010, the GC-2014 gives best results for routine analysis for a good price-performance ratio. The GC-2014 Series is equipped with the advanced flow controller (AFC) technology inherited from the GC-17A Series and GC-2010 Series. This digital control is standard for not only capillary columns, but packed columns as well. Accurate flow rate control via AFC has higher-level repeatability of retention time and peak area, enabling a higher level of analyses. The detectors have been completely redesigned, incorporating the GC-2010 detector designs for capillary analyses and the GC-14 detector designs for packed columns. This TCD-2014 unit is ideal for packed column measurements employing the semi-diffusion cell design used in TCD-14. The newly designed FPD-2014 takes advantage of the holophotal construction of the FPD-2010.Select from four types of injection units and five types of detectors per the target compounds and analysis objective. Modular injection units, detectors and auto-injectors can be easily added after installing the unit in your lab. Three Injection Units and Four Detectors can be simultaneously installed.
Shimadzu’s new-generation GC-2025 capillary gas chromatograph minimizes environmental impact by reducing power and carrier gas consumption while retaining the performance capabilities required for capillary analysis. The GC-2025 incorporates a digital flow controller that controls both the carrier and detector gases and a newly designed energy-saving column oven that features small volume and less heating loss, realizing a dramatic improvement in operation costs. The compact GC-2025 is the gas chromatograph for environmentally friendly, high value performance. Heat losses are significantly reduced through high-performance insulation and a smaller oven size to reduce the heating requirements. In addition, it incorporates an energy-saving heater to further cut power costs, The GC-2025 adopts the same well-proven electronic flow controllers (AFC/APC) for carrier gas and detector gas control that are used in the GC-2010 Plus. They offer highly accurate flow control to achieve excellent reproducibility.
There is increasing public interest in the analysis of trace compounds that contribute to environmental pollution, affect human health and in research related to novel compounds. Reducing running costs and lessening the impact on the environment by increasing analytical efficiency and decreasing power consumption are universal goals. The GCMS-QP2010 Ultra was developed by engineers who accepted the challenge to meet these needs.
* Based on our specified conditions
** Compared with previous model
Achieves a maximum scan speed of 20,000 u/sec ASSP™ technology provides greater sensitivity Ultra-fast data acquisition rates ideal for comprehensive GC×GC and Fast-GC
Analysis cycle time cut in half*
Significantly reduced maintenance downtime* Easy exchange of columns for improved productivity*
36% reduction in power consumption in analysis standby mode*
30% reduction in CO2 factory emissions
The GCMS-QP2010SE is our advanced standard gas chromatograph mass spectrometer. Descended from the GCMS-QP2010S, it combines the benefits of economy, simple operation, and enhanced performance. The enhanced maximum column flow enables a variety of columns to be selected. Productivity and sample throughput can be dramatically increased. Ecology mode saves power and carrier gas consumption allowing for a lower cost of ownership and less environmental stress.
The importance of high-performance analytical instruments for monitoring microscopic quantities of compounds related to environmental pollution and human health, and for developing and evaluating new, highly functional materials and chemical products continues to grow. The GCMS-QP2020 has been designed to meet these needs. Featuring enhanced instrument functionality, analysis software, databases, and a sample introduction system, the GCMS-QP2020 will help maximize the capabilities of your laboratory. The vacuum exhaust system, which features a new differential exhaust turbomolecular pump, achieves the highest sensitivity under all GCMS conditions. In addition to helium, it can be operated with confidence using hydrogen or nitrogen as the carrier gas, which helps reduce operational costs. In addition, analysis times can be shortened while retaining high speed and high sensitivity, which contributes to the optimization of laboratory productivity.